Why Does Mycobacterium Vaccae Make You Happy? This soil microbe is known to boost the levels of serotonin and other brain cytokines and may have a positive effect on mood and anxiety. It has also been used as a mood enhancer for lung cancer patients. Researchers say that it activates brain cells that produce serotonin, and alters behavior similar to antidepressants. This makes it a good addition to your daily diet.
Why Does Mycobacterium Vaccae Make You Happy?
The soil microbe Mycobacterium vaccae helps the brain release serotonin, a chemical that makes us happy. It also causes the blood vessels to constrict, making us feel calm. Serotonin levels are important for brain health and mood regulation, and a deficiency can lead to depression and anxiety. Researchers at University College London found that M. vaccae increased serotonin levels in mice, and lowered their anxiety.
The bacteria were injected into mice. After a week, the mice showed a marked decrease in stress. The mice acted as though they were on an antidepressants mycobacterium vaccae supplement. They also showed less system-wide inflammation. The bacteria were also shown to increase the expression of a gene called tph2, which helps make serotonin. This protein, in turn, modulates mood and anxiety.
In a recent study, researchers found that a bacteria called Mycobacterium vaccae can dampen inflammation in the brain. The bacteria have also been found to reduce anxiety and stress. Currently, Lowry is pursuing the development of this bacteria as a drug. He hopes to start clinical trials with this bacteria for patients with mental illness and those at risk for PTSD. The bacteria may be especially useful for soldiers preparing for deployment or emergency room workers.
The bacteria induce anti-inflammatory immune responses in the hippocampus. They also inhibit the priming of microglial cells in response to a stressful event. This may help explain why the bacteria reduce anxiety. A recent study in mice found that Mycobacterium vaccae reduces anxiety and stress. The mice were injected with Mycobacterium vaccae, which suppresses the release of alarmins, which are released when the brain senses a threat.
Increases brain cytokines
The immune system’s response to Mycobacterium vaccae can be a therapeutic tool for the treatment of neuroinflammation. The organism induces a reduction in CD200/CD200R1 signaling, which drives disinhibition of innate immune response, and increases the production of anti-inflammatory cytokines. These results suggest that peripheral immunization with M. vaccae may enhance CNS immunity by stimulating the influx of T cells and promoting an anti-inflammatory milieu.
The bacteria is innocuous and is naturally found in soil. The bacteria is commonly used to treat skin allergies and can improve mood. However, immunologists and neuroscientists have only recently figured out why it works. Specifically, the bacteria induce the release of chemicals called cytokines that activate immune cells and act on receptors on sensory nerves. Because of this, it may be used to treat depression.
The bacteria Mycobacterium vaccae is a saprophytic, non-pathogenic bacterial species with immunoregulatory, anti-inflammatory, and antidepressant properties. It is ubiquitous in the environment and has been found to enhance the differentiation of regulatory T cells. However, the exact mechanism of how Mycobacterium vaccae increases mood is still unclear. However, it does appear to have the potential to improve mood.
In a study published in the journal Neuroscience, researchers showed that Mycobacterium vaccae increased mood in laboratory mice in a similar way to antidepressants. They found that the bacteria activated brain cells that secrete serotonin, a neurotransmitter associated with happiness. Low levels of serotonin have been linked to depression and anxiety. So, Mycobacterium vaccae may be a natural antidepressant without any negative side effects.
The study conducted by Lowry and colleagues examined whether Mycobacterium vaccae boosts the brain’s performance by dampening inflammation. The team hopes to obtain Investigational New Drug (IND) status for the bacterium and conduct clinical trials. Potential patients might include soldiers preparing for deployment or emergency room staff. The results of this study are expected to lead to new treatments for a variety of conditions.
The symbiotic relationship between microbes and hosts helps animals survive in their environment and fight pathogens. The contact between host and tolerogenic microbes is essential for proper functioning of the gut-brain-microbiota axis, which regulates behavior and emotion. The researchers found that treatment with Mycobacterium vaccae reduced anxiety-related behaviors in mice and increased their performance in maze tests.